CAMK2G

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesCAMK2G, CAMK, CAMK-II, CAMKG, calcium/calmodulin dependent protein kinase II gamma
Quick facts Available structures, PDB ...
CAMK2G
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCAMK2G, CAMK, CAMK-II, CAMKG, calcium/calmodulin dependent protein kinase II gamma
External IDsOMIM: 602123; MGI: 88259; HomoloGene: 15596; GeneCards: CAMK2G; OMA:CAMK2G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039138
NM_001039139
NM_178597
NM_001360186

RefSeq (protein)

NP_001034227
NP_001034228
NP_848712
NP_001347115

Location (UCSC)Chr 10: 73.81 – 73.87 MbChr 14: 20.73 – 20.79 Mb
PubMed search[3][4]
Wikidata
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Function

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined.[6]

Interactions

CAMK2G has been shown to interact with RRAD.[7]

See also

References

Further reading

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