Collectin-12

Protein found in humans From Wikipedia, the free encyclopedia

Collectin-12, also known as collectin subfamily member 12, is a collectin protein that in humans is encoded by the COLEC12 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesCOLEC12, CLP1, NSR2, SCARA4, SRCL, collectin subfamily member 12
Quick facts COLEC12, Available structures ...
COLEC12
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCOLEC12, CLP1, NSR2, SCARA4, SRCL, collectin subfamily member 12
External IDsOMIM: 607621; MGI: 2152907; HomoloGene: 34248; GeneCards: COLEC12; OMA:COLEC12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030781
NM_130386

NM_130449

RefSeq (protein)

NP_569057

NP_569716

Location (UCSC)Chr 18: 0.32 – 0.5 MbChr 18: 9.71 – 9.88 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the collectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. [provided by RefSeq, May 2018].

References

Further reading

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