CCP110

CCP110
Identifiers
Aliases	CCP110, CP110, Cep110, centriolar coiled-coil protein 110kDa, centriolar coiled-coil protein 110
External IDs	OMIM: 609544; MGI: 2141942; HomoloGene: 8810; GeneCards: CCP110; OMA:CCP110 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	19,553,408 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	118,336,247 bp
RNA expression pattern
	Top expressed in
	optic nerve; ; corpus callosum; ; globus pallidus; ; internal globus pallidus; ; external globus pallidus; ; buccal mucosa cell; ; bronchial epithelial cell; ; inferior ganglion of vagus nerve; ; pars reticulata; ; subthalamic nucleus;
	Top expressed in
	superior cervical ganglion; ; olfactory epithelium; ; zygote; ; hand; ; spermatocyte; ; seminiferous tubule; ; secondary oocyte; ; lateral geniculate nucleus; ; globus pallidus; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cell projection; cytosol; centriole; cytoplasm; centrosome; cilium; microtubule organizing center; cytoskeleton; protein-containing complex;
Biological process	cell projection organization; G2/M transition of mitotic cell cycle; negative regulation of cilium assembly; centriole replication; positive regulation of cilium assembly; ciliary basal body organization; centrosome duplication; regulation of cytokinesis; protein deubiquitination; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	9738
	101565
	ENSG00000103540
	ENSMUSG00000033904
	O43303
	Q7TSH4
NM_001199022; NM_014711; NM_001323569; NM_001323570; NM_001323571;
	NM_001323572; NM_001323576; NM_001323577
	NM_182995; NM_001360793; NM_001360794
NP_001185951; NP_001310498; NP_001310499; NP_001310500; NP_001310501;
	NP_001310505; NP_001310506; NP_055526
	NP_892040; NP_001347722; NP_001347723
	Wikidata
View/Edit Human	View/Edit Mouse

Centriolar coiled-coil protein of 110 kDa also known as centrosomal protein of 110 kDa or CP110 is a protein that in humans is encoded by the CCP110 gene. It is a cell cycle-dependent CDK substrate and regulates centrosome duplication.^[5]^[6] CP110 suppresses a cilia assembly program.^[7]