Chymotrypsin C is a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity.[5] In other words, it is involved in breaking peptide bonds in proteins. It catalyzes the preferential cleavage of peptide bonds from the following amino acids:
- Leu┼, Tyr┼, Phe┼, Met┼, Trp┼, Gln┼, Asn┼
This is enzyme activity is similar to chymotrypsin A/B (EC 3.4.21.1), but with some differences such as a preference for breaking leucine over phenylalanine bonds.[8]
A protein with similar enzyme activity can also be formed from pig chymotrypsinogen C and cattle subunit II of procarboxypeptidase A.[9][10][11]
