Renal collecting duct carcinoma
Type of kidney cancer
From Wikipedia, the free encyclopedia
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers.[2] It is also recently described; a 2002 review found just 40 case reports worldwide.[3] Previously, due to its location, CDC was commonly diagnosed as renal cell carcinoma or a subtype of renal cell carcinoma.[4] However, CDC does not respond well to chemotherapy drugs used for renal cell carcinoma, and progresses and spreads more quickly.
Signs and symptoms
Signs and symptoms are as for kidney cancer.[citation needed]
Histology
Histologic examination of collecting duct carcinoma demonstrates an infiltrative lesion with tubulopapillary, irregular channels lined by high grade hobnail cells with marked desmoplastic response and brisk neutrophilic infiltrate.[citation needed]
History
CDC was thought to be renal cell carcinoma, until "recently developed techniques of lectin histochemistry" helped forward knowledge of kidney duct cancers.[5]
See also
- Chemotherapy
- Renal cell carcinoma, clear cell renal carcinoma, types of kidney cancer
- Surface epithelial-stromal tumor (a type of ovarian cancer which affects the epithelial cells