Cornelius O'Brien (4 May 1843 – 9 March 1906) was a Canadian Roman Catholic priest, archbishop, and author of 39 books.
Born in New Glasgow, Prince Edward Island, the son of Terence O'Brien and Catherine O'Driscoll, O'Brien graduated from Urban College and in 1871 was ordained a priest. Upon returning to Canada, he was appointed a professor in St. Dunstan's College and rector of the Cathedral of Charlottetown, but failing health in 1874 led to his transfer to the country parish of Indian River, where O'Brien devoted his leisure to writing, publishing The Philosophy of the Bible vindicated (Charlottetown, 1876); Early Stages of Christianity in England (Charlottetown, 1880); and Mater Admirablia (Montreal, 1882).
He also wrote St. Agnes, Virgin and Martyr (Halifax, 1887), Aminta, a modern life drama (1890), and Memoirs of Edmund Burke, the first Bishop of Halifax (1894).