Deoxycytidine diphosphate
Chemical compound
From Wikipedia, the free encyclopedia
Deoxycytidine diphosphate is a nucleoside diphosphate. It is related to the common nucleic acid CTP, or cytidine triphosphate, with the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose removed (hence the deoxy- part of the name), and with one fewer phosphoryl group than CTP .
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| Names | |
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| IUPAC name
2′-Deoxycytidine 5′-(trihydrogen diphosphate) | |
| Systematic IUPAC name
[(2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl trihydrogen diphosphate | |
| Other names
2'-Deoxycytidine diphosphate | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| MeSH | deoxycytidine+diphosphate |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C9H15N3O10P2 | |
| Molar mass | 387.178 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2'-Deoxycytidine diphosphate is abbreviated as dCDP.[1]
Synthesis of cytidine nucleotides
Deoxycytidine diphosphate is synthesized through the oxidation-reduction reaction of cytidine 5'-diphosphocholine which is catalyzed by the presence of ribonucleoside-diphosphate reductase.[2] Additionally, ribonucleoside-diphosphate reductase is capable of binding and catalyzing both the formation of deoxyribonucleotides from ribonucleotide.[3]