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Dapagliflozin/saxagliptin

Combination drug From Wikipedia, the free encyclopedia


Dapagliflozin/saxagliptin, sold under the brand name Qtern, is a fixed-dose combination anti-diabetic medication used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.[2][3] It is a combination of dapagliflozin and saxagliptin.[2][3] It is taken by mouth.[2][3]

Quick facts Combination of, Saxagliptin ...
Dapagliflozin/saxagliptin
Combination of
DapagliflozinSGLT-2 inhibitor
SaxagliptinDipeptidyl peptidase-4 inhibitor
Clinical data
Trade namesQtern
AHFS/Drugs.comProfessional Drug Facts
License data
Pregnancy
category
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG
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The most common side effects include upper respiratory tract infection (such as nose and throat infections) and, when used with a sulphonylurea, hypoglycaemia (low blood glucose levels).[3]

Dapagliflozin/saxagliptin was approved for medical use in the European Union in July 2016, and in the United States in February 2017.[3][4]

Medical uses

In the United States, dapagliflozin/saxagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.[2]

In the European Union, it is indicated in adults aged 18 years and older with type 2 diabetes:

  • to improve glycemic control when metformin with or without sulphonylurea (SU) and either saxagliptin or dapagliflozin does not provide adequate glycemic control.[3]
  • when already being treated with saxagliptin and dapagliflozin.[3]

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