5α-Dihydrocorticosterone

5α-Dihydrocorticosterone
Names
	IUPAC name 11β,21-Dihydroxy-5α-pregnane-3,20-dione
	Systematic IUPAC name (1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one
Identifiers
CAS Number	298-25-9;
3D model (JSmol)	Interactive image;
ChemSpider	2338305;
PubChem CID	3080546;
CompTox Dashboard (EPA)	DTXSID80952235 ;
	InChI InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12,14-17,19,22,24H,3-11H2,1-2H3/t12-,14-,15-,16+,17-,19+,20-,21-/m0/s1;
	SMILES CC12CCC(=O)CC1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O;
Properties
Chemical formula	C21H32O4
Molar mass	348.47638 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

5α-Dihydrocorticosterone (5α-DHC, 5α-DHB), also known as 11β,21-dihydroxy-5α-pregnane-3,20-dione, is a naturally occurring, endogenous glucocorticoid steroid hormone and neurosteroid.^[1]^[2]^[3] It is biosynthesized from corticosterone by the enzyme 5α-reductase.^[4]^[5]^[6] DHC has central depressant effects and impairs long-term potentiation in animals.^[7]^[8]

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