Dimethylmaleate hydratase
Class of enzymes
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The enzyme dimethylmaleate hydratase (EC 4.2.1.85) catalyzes the chemical reaction
- (2R,3S)-2,3-dimethylmalate dimethylmaleate + H2O
| dimethylmaleate hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.85 | ||||||||
| CAS no. | 93229-56-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming). This enzyme is also called (2R,3S)-2,3-dimethylmalate hydro-lyase. This enzyme participates in c5-branched dibasic acid metabolism. It employs one cofactor, iron.
References
- Kollmann-Koch A, Eggerer H (1984). "Nicotinic acid metabolism. Dimethylmaleate hydratase". Hoppe-Seyler's Z. Physiol. Chem. 365 (8): 847â57. doi:10.1515/bchm2.1984.365.2.847. PMID 6489933.
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