Draft:Biobank Ireland Trust
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Biobank Ireland Trust, established in 2004, is dedicated to advancing cancer research by developing a network of biobanks across Ireland. It collects, stores, and shares high-quality human tissue samples for ethically approved research projects, in order to improve understanding of cancer’s molecular mechanisms, treatment response, and resistance. By connecting hospitals and researchers, Biobank Ireland facilitates collaborations that drive the discovery of more effective, targeted treatments. The organisation plays a key role in promoting best practices in biobanking, ensuring equitable access to samples, and engaging the public and government on the critical role biobanks play in medical research.
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| Established | 2004 |
|---|---|
| Type | Nonprofit organization |
| Purpose | Healthcare and research |
| Headquarters | Dublin, Ireland |
| Website | https://biobankireland.com/ |
Role
Biobank Ireland supports other biobanks by providing access to its Biobank Information Management System (BIMS), offering grants and sponsorship for essential equipment, and developing standardised operating procedures (SOPs). This ensures best practices, enhances collaboration, and promotes consistent, high-quality research across institutions.
Research
Biobanks are at the forefront of medical innovation by providing researchers with high-quality, well-preserved samples. These samples enable the identification of biomarkers and genetic predispositions linked to diseases like cancer and cardiovascular conditions. This access enables comprehensive studies into the causes of diseases and how they evolve. By contributing to large-scale studies and clinical trials, biobanks facilitate the development of new diagnostic tools and therapies, driving continuous advancements in health science.
Research Projects
Breast Predict: since 2003, Biobank Ireland Trust has been involved in collecting tumour samples and data from nearly every breast cancer patient in Ireland with their consent. The study found that women regularly taking aspirin before their breast cancer diagnosis are less likely to experience cancer spread to lymph nodes, significantly improving survival rates.
HPV and Cervical Cancer Study: Since 2018, this ongoing study has examined the link between HPV infections and cervical cancer, which accounts for nearly all cervical cancer cases.
Small Cell Lung Cancer (SCLC) Study (2018): A multinational, multi-centre study analysing gene expression in small cell lung cancer. Early findings suggest 80-85% of patients may have specific expressed genes. These results are expected to guide gene therapy and new treatments
Prostate Cancer Studies - IRONMAN Prostate Cancer Study: Examined care and treatment variations to improve clinical outcomes by enrolling 5,000 men worldwide with metastatic hormone-sensitive or castration-resistant prostate cancer.
ENZAMET and ENZARAD Clinical Trials: Biobank Ireland has handled sample management and redistribution to Australia for further research. The trials are exploring new treatments for prostate cancer with Cancer Trials Ireland and St. James’ Hospital.
Data sharing & Integration
Biobank Ireland promotes data sharing and integration through the Biobank Information Management System (BIMS), providing access to a large database for researchers and organisations to advance scientific research.
History
2004
Biobank Ireland Trust is established in Dublin, with the aim of advancing cancer research.
2012
Federated Biobank Model launched to promote collaboration across Ireland's healthcare and research sectors.
2016
Expanded focus beyond cancer to include other diseases, aligning with advancements in personalised medicine.
Initial design of the Shared Campus Biobank developed by Biobank Ireland trust to house SJH Histopathology Cancer Biobank.
2020
During the COVID-19 pandemic, Biobank Ireland provided research support on viral and immunological responses.
Partners
- St. James's Hospital
- St. Vincent's University Hospital
- Galway University Hospital
- Cork University Hospital
- Queen's University Belfast
- Trinity St. James's Cancer Institute
- National Biobank Working Group
- Health Research Charities Ireland
- Cancer Trials Ireland
- National Institute
- Irish Cancer Society
- Blood Cancer Network Ireland
- ISBER