Nifoxipam

Nifoxipam (3-hydroxydesmethylflunitrazepam, DP 370) is a benzodiazepine that is a minor metabolite of flunitrazepam and has been sold online as a designer drug.^{[1][2][3][4][5][6][7][8][9]}

Legal status

• AU: Unscheduled
• BR: Class B1 (Psychoactive drugs)
• CA: Schedule IV
• DE: NpSG (Industrial and scientific use only)
• UK: Under Psychoactive Substances Act
• US: Unscheduled
• UN: Unscheduled
• In general legal for medical and research uses.

CAS Number

• 74723-10-7

PubChem CID

• 3058221

ChemSpider

• 2319383

Quick facts Legal status, Identifiers ...

Nifoxipam

Legal status
Legal status	AU: Unscheduled BR: Class B1 (Psychoactive drugs) CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act US: Unscheduled UN: Unscheduled In general legal for medical and research uses.
Identifiers
IUPAC name 5-(2-fluorophenyl)-3-hydroxy-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
CAS Number	74723-10-7
PubChem CID	3058221
ChemSpider	2319383
UNII	9O6C9M3CH6
CompTox Dashboard (EPA)	DTXSID80996250
ECHA InfoCard	100.440.630
Chemical and physical data
Formula	C15H10FN3O4
Molar mass	315.260 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1C(O)N=C(C2=CC=CC=C2F)C3=CC([N+]([O-])=O)=CC=C3N1
InChI InChI=1S/C15H10FN3O4/c16-11-4-2-1-3-9(11)13-10-7-8(19(22)23)5-6-12(10)17-14(20)15(21)18-13/h1-7,15,21H,(H,17,20) Key:UHFIFTRHLBAWGY-UHFFFAOYSA-N

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Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to lormetazepam and flunitrazepam in mice.^[1]