NFIL3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene.[5]

AliasesNFIL3, E4BP4, IL3BP1, NF-IL3A, NFIL3A, nuclear factor, interleukin 3 regulated
End91,423,832 bp[1]
Quick facts Identifiers, Aliases ...
NFIL3
Identifiers
AliasesNFIL3, E4BP4, IL3BP1, NF-IL3A, NFIL3A, nuclear factor, interleukin 3 regulated
External IDsOMIM: 605327; MGI: 109495; HomoloGene: 3928; GeneCards: NFIL3; OMA:NFIL3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005384
NM_001289999
NM_001290000

NM_017373

RefSeq (protein)

NP_001276928
NP_001276929
NP_005375

NP_059069

Location (UCSC)Chr 9: 91.41 – 91.42 MbChr 13: 53.12 – 53.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

Expression of interleukin-3 (IL-3) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site.[5][6]

References

Further reading

Related Articles

Wikiwand AI