4-hydroxybenzoate polyprenyltransferase
Class of enzymes
From Wikipedia, the free encyclopedia
In enzymology, a 4-hydroxybenzoate polyprenyltransferase (EC 2.5.1.39) is an enzyme that catalyzes the chemical reaction
- a polyprenyl diphosphate + 4-hydroxybenzoate diphosphate + a 4-hydroxy-3-polyprenylbenzoate
| 4-hydroxybenzoate polyprenyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.39 | ||||||||
| CAS no. | 9030-77-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are a polyprenyl diphosphate and 4-hydroxybenzoate, whereas its two products are diphosphate and 4-hydroxy-3-polyprenylbenzoate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in ubiquinone biosynthesis.[1]
Nomenclature
The systematic name of this enzyme class is polyprenyl-diphosphate:4-hydroxybenzoate polyprenyltransferase. Other names in common use include:
- nonaprenyl-4-hydroxybenzoate transferase,
- 4-hydroxybenzoate transferase,
- p-hydroxybenzoate dimethylallyltransferase,
- p-hydroxybenzoate polyprenyltransferase,
- p-hydroxybenzoic acid-polyprenyl transferase,
- p-hydroxybenzoic-polyprenyl transferase, and
- 4-hydroxybenzoate nonaprenyltransferase
