EIF2S3

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 2 subunit 3 (eIF2γ) is a protein that in humans is encoded by the EIF2S3 gene.[5][6][7]

AliasesEIF2S3, EIF2, EIF2G, EIF2gamma, eIF-2gA, eukaryotic translation initiation factor 2 subunit gamma, MRXSBRK, MEHMO
End24,078,810 bp[1]
Quick facts Identifiers, Aliases ...
EIF2S3
Identifiers
AliasesEIF2S3, EIF2, EIF2G, EIF2gamma, eIF-2gA, eukaryotic translation initiation factor 2 subunit gamma, MRXSBRK, MEHMO
External IDsOMIM: 300161; MGI: 1349431; HomoloGene: 90888; GeneCards: EIF2S3; OMA:EIF2S3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001415

NM_012010

RefSeq (protein)

NP_001406

NP_036140

Location (UCSC)Chr X: 24.05 – 24.08 MbChr X: 93.23 – 93.26 Mb
PubMed search[3][4]
Wikidata
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Function

Eukaryotic translation initiation factor 2 (eIF2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. eIF2 is composed of three subunits, alpha (α), beta (β), and gamma (γ, this article), with the protein encoded by this gene representing the gamma subunit.[7]

See also

References

Further reading

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