Edward Fryer, M.D. (1761–1826) was an English physician.
Fryer was born at Frome, Somerset. He was sent to the grammar school there, and then apprenticed to a general practitioner of medicine in Wiltshire. He studied medicine in London, Edinburgh, and Leyden, and graduated M.D. at the University of Leyden 29 January 1785. He travelled in Europe until 1790, when he came to London, and was admitted a licentiate of the Royal College of Physicians.