Chemokine-like protein TAFA-1 is a protein that in humans is encoded by the TAFA1 gene.[5][6]

AliasesTAFA1, TAFA-1, Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1, family with sequence similarity 19 member A1, C-C motif chemokine like, FAM19A1, TAFA chemokine like family member 1 Quick facts TAFA1, Identifiers ...
| TAFA1 |
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| Identifiers |
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| Aliases | TAFA1, TAFA-1, Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1, family with sequence similarity 19 member A1, C-C motif chemokine like, FAM19A1, TAFA chemokine like family member 1 |
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| External IDs | OMIM: 617495; MGI: 2443695; GeneCards: TAFA1 |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - middle temporal gyrus
- endothelial cell
- Brodmann area 23
- pons
- Brodmann area 46
- superior frontal gyrus
- entorhinal cortex
- postcentral gyrus
- primary visual cortex
- dorsolateral prefrontal cortex
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| | Top expressed in | - piriform cortex
- subdivision of hippocampus
- Region I of hippocampus proper
- hippocampus proper
- lumbar spinal ganglion
- dentate gyrus
- pontine nuclei
- dentate gyrus of hippocampal formation granule cell
- primary visual cortex
- amygdala
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| | More reference expression data |
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| BioGPS | |
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| Wikidata |
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Close
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells.[6]