Censavudine

Investigational new anti-HIV drug From Wikipedia, the free encyclopedia

Censavudine (INN;[1] development code BMS-986001) is an investigational new drug being developed by Bristol Myers-Squibb for the treatment of HIV infection.[2][3] It was originally developed at Yale University.[4] It is still in an investigational phase of development as of 2023.[5]

Other names4'-ethynylstavudine, festinavir
Legal status
  • Investigational
Quick facts Clinical data, Other names ...
Censavudine
Clinical data
Other names4'-ethynylstavudine, festinavir
Legal status
Legal status
  • Investigational
Identifiers
  • 1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
NIAID ChemDB
CompTox Dashboard (EPA)
ECHA InfoCard100.225.812 Edit this at Wikidata
Chemical and physical data
FormulaC12H12N2O4
Molar mass248.238 g·mol−1
3D model (JSmol)
  • CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@](O2)(CO)C#C
  • InChI=1S/C12H12N2O4/c1-3-12(7-15)5-4-9(18-12)14-6-8(2)10(16)13-11(14)17/h1,4-6,9,15H,7H2,2H3,(H,13,16,17)/t9-,12+/m1/s1
  • Key:OSYWBJSVKUFFSU-SKDRFNHKSA-N
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Renaming

Until 2013, censavudine has been known as festinavir, but the name was changed to avoid confusion with HIV protease inhibitors which all bear class suffix "–navir" (e.g. tipranavir, lopinavir, saquinavir, etc.).[5]

References

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