Flavanone 7-O-beta-glucosyltransferase
Class of enzymes
From Wikipedia, the free encyclopedia
Flavanone 7-O-beta-glucosyltransferase (EC 2.4.1.185) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + a flavanone UDP + a flavanone 7-O-beta-D-glucoside
| Flavanone 7-O-beta-glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.185 | ||||||||
| CAS no. | 125752-73-0 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The two substrates of this enzyme are UDP-glucose and a flavanone. Its products are UDP and the corresponding flavanone 7-O-beta-D-glucoside.[1][2]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-flavanone 7-O-glucosyltransferase, naringenin 7-O-glucosyltransferase, and hesperetin 7-O-glucosyl-transferase.[1]
An example of this reaction in flavonoid biosynthesis is the conversion of naringenin to prunin:[3]
In some citrus fruits, the product prunin is converted to naringin, a compound which is responsible for the bitter taste of grapefruit.[3][4]
