Galanin receptor 1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene.[5]

AliasesGALR1, GALNR, GALNR1, Galanin receptor 1
End77,277,900 bp[1]
Quick facts GALR1, Identifiers ...
GALR1
Identifiers
AliasesGALR1, GALNR, GALNR1, Galanin receptor 1
External IDsOMIM: 600377; MGI: 1096364; HomoloGene: 74396; GeneCards: GALR1; OMA:GALR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001480

NM_008082

RefSeq (protein)

NP_001471

NP_032108

Location (UCSC)Chr 18: 77.25 – 77.28 MbChr 18: 82.41 – 82.42 Mb
PubMed search[3][4]
Wikidata
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Function

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-trans membrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the GI/GO family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.[5]

See also

References

Further reading

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