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Gamma-glutamyltransferase 6

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Gamma-glutamyltransferase 6 is a protein that in humans is encoded by the GGT6 gene.[5]

AliasesGGT6, gamma-glutamyltransferase 6
External IDsOMIM: 612341; MGI: 1918772; GeneCards: GGT6
End4,560,818 bp[1]
Quick facts GGT6, Identifiers ...
GGT6
Identifiers
AliasesGGT6, gamma-glutamyltransferase 6
External IDsOMIM: 612341; MGI: 1918772; GeneCards: GGT6
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
2.3.2.2↗↗↗↗
3.4.19.13↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_153338
NM_001122890
NM_001288702
NM_001288703
NM_001288704

NM_027819

RefSeq (protein)

NP_001116362
NP_001275631
NP_001275632
NP_001275633
NP_699169

NP_082095

Location (UCSC)Chr 17: 4.56 – 4.56 MbChr 11: 72.33 – 72.33 Mb
PubMed search[3][4]
Wikidata
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Function

GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).

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