Gastrokine-1

Gastrokine-1 is a protein that in humans is encoded by the GKN1 gene.^[5][6][7]

AliasesGKN1, AMP18, BRICD1, CA11, FOV, foveolin, gastrokine 1

External IDsOMIM: 606402; MGI: 1913533; HomoloGene: 10487; GeneCards: GKN1; OMA:GKN1 - orthologs

Chr.Chromosome 2 (human)^[1]

End68,980,980 bp^[1]

Quick facts GKN1, Identifiers ...

GKN1
Identifiers
Aliases	GKN1, AMP18, BRICD1, CA11, FOV, foveolin, gastrokine 1
External IDs	OMIM: 606402; MGI: 1913533; HomoloGene: 10487; GeneCards: GKN1; OMA:GKN1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p13.3 Start 68,974,573 bp[1] End 68,980,980 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 D1 Start 87,322,632 bp[2] End 87,327,924 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa pylorus cardia mucosa of ileum body of stomach fundus decidua left adrenal gland right adrenal cortex left adrenal cortex Top expressed in epithelium of stomach mucous cell of stomach pyloric antrum duodenum interventricular septum esophagus decidua cornea jejunum islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function molecular function Cellular component extracellular region extracellular space cellular component Biological process digestion positive regulation of cell division regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56287 66283 Ensembl ENSG00000169605 ENSMUSG00000030050 UniProt Q9NS71 Q9CR36 RefSeq (mRNA) NM_019617 NM_025466 RefSeq (protein) NP_062563 NP_079742 Location (UCSC) Chr 2: 68.97 – 68.98 Mb Chr 6: 87.32 – 87.33 Mb PubMed search [3] [4]
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The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.^[7]