Glassy cell carcinoma of the cervix

Medical condition From Wikipedia, the free encyclopedia

Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour of the uterine cervix.[1] The tumour gets its name from its microscopic appearance; its cytoplasm has a glass-like appearance.

Other namesGlassy cell carcinoma
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Glassy cell carcinoma of the cervix
Other namesGlassy cell carcinoma
Micrograph of a glassy cell carcinoma of the cervix. H&E stain.
SpecialtyOncology Edit this on Wikidata
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Signs and symptoms

The signs and symptoms are similar to other cervical cancers and may include post-coital bleeding and/or pain during intercourse (dyspareunia). Early lesions may be completely asymptomatic.[citation needed]

Cause

Diagnosis

The diagnosis is based on tissue examination, e.g. biopsy.[citation needed]

Under the microscope, glassy cell carcinoma tumours are composed of cells with a glass-like cytoplasm, typically associated with an inflammatory infiltrate abundant in eosinophils and very mitotically active. PAS staining highlights the plasma membrane.[2]

Treatment

The treatment is dependent on the stage. Advanced tumours are treated with surgery (radical hysterectomy and bilateral salpingo-opherectomy), radiation therapy and chemotherapy.[2]

See also

Additional images

References

Further reading

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