B-1,4-mannosyl-glycoprotein 4-b-N-acetylglucosaminyltransferase
Class of enzymes
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Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144, N-acetylglucosaminyltransferase III, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III, beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, GnTIII) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R
| Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.144 | ||||||||
| CAS no. | 83744-93-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.
