HIST1H2BH

Histone H2B type 1-H is a protein that in humans is encoded by the HIST1H2BH gene.^[5][6][7]

AliasesH2BC9, H2B/j, H2BFJ, histone cluster 1, H2bh, histone cluster 1 H2B family member h, HIST1H2BH, H2B clustered histone 9

External IDsOMIM: 602806; MGI: 3710645; HomoloGene: 134772; GeneCards: H2BC9; OMA:H2BC9 - orthologs

Chr.Chromosome 6 (human)^[1]

End26,252,075 bp^[1]

Quick facts H2BC9, Identifiers ...

H2BC9
Identifiers
Aliases	H2BC9, H2B/j, H2BFJ, histone cluster 1, H2bh, histone cluster 1 H2B family member h, HIST1H2BH, H2B clustered histone 9
External IDs	OMIM: 602806; MGI: 3710645; HomoloGene: 134772; GeneCards: H2BC9; OMA:H2BC9 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.2 Start 26,251,614 bp[1] End 26,252,075 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A3.1 Start 22,017,913 bp[2] End 22,021,700 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cell monocyte jejunal mucosa mucosa of transverse colon right ventricle thymus bronchial epithelial cell embryo cartilage tissue mucosa of sigmoid colon Top expressed in granulocyte embryo genital tubercle tail of embryo bone marrow zygote mesencephalon esophagus ileum conceptus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein heterodimerization activity protein binding enzyme binding ubiquitin-like protein ligase binding STAT family protein binding Cellular component chromosome nucleosome extracellular exosome nucleus nucleoplasm cytosol protein-containing complex Biological process nucleosome assembly protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8345 665622 Ensembl ENSG00000275713 ENSMUSG00000069303 UniProt Q93079 P10853 RefSeq (mRNA) NM_003524 NM_001110555 NM_001313878 RefSeq (protein) NP_003515 NP_835505 NP_001091448 NP_001300809 NP_001104025 NP_001300807 NP_835502 NP_835506 NP_835508 Location (UCSC) Chr 6: 26.25 – 26.25 Mb Chr 13: 22.02 – 22.02 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.^[7]