Influenza A virus subtype H6N2
Avian influenza virus
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H6N2 is an avian influenza virus with two forms: one has a low and the other a high pathogenicity. It can cause a serious problem for poultry, and also infects ducks as well.[1] H6N2 subtype is considered to be a non-pathogenic chicken virus, the host still unknown, but could strain from feral animals, and/or aquatic bird reservoirs.[2] H6N2 along with H6N6 are viruses that are found to replicate in mice without preadaptation, and some have acquired the ability to bind to human-like receptors.[3] Genetic markers for H6N2 include 22-amino acid stalk deletion in neuraminidase (NA) protein gene, increased N-glycosylation, and a D144 mutation of the Haemagglutinin (HA) protein gene.[4] Transmission of avian influenza viruses from wild aquatic birds to domestic birds usually cause subclinical infections, and occasionally, respiratory disease and drops in egg production.[5] Some histological features presented in chicken infected with H6N2 are fibrinous yolk peritonitis, salpingitis, oophoritis, nephritis, along with swollen kidneys as well.[6]
| Influenza A virus subtype H6N2 | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Insthoviricetes |
| Order: | Articulavirales |
| Family: | Orthomyxoviridae |
| Genus: | Alphainfluenzavirus |
| Species: | |
| Serotype: | Influenza A virus subtype H6N2 |
Signs and symptoms
- sneezing and lacrimation
- prostration
- anorexia and fever
- sometimes swelling of the infraorbital sinuses with nasal mucous [7]