IMPDH/GMPR family
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| IMP dehydrogenase / GMP reductase domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
binary complex of human type-i inosine monophosphate dehydrogenase with 6-cl-imp | |||||||||
| Identifiers | |||||||||
| Symbol | IMPDH | ||||||||
| Pfam | PF00478 | ||||||||
| Pfam clan | CL0036 | ||||||||
| InterPro | IPR001093 | ||||||||
| PROSITE | PDOC00391 | ||||||||
| SCOP2 | 1ak5 / SCOPe / SUPFAM | ||||||||
| |||||||||
In molecular biology, the IMPDH/GMPR family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism. These enzymes adopt a TIM barrel structure.[1][2]