Inositol-1,3,4-trisphosphate 5/6-kinase
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inositol-1,3,4-trisphosphate 5/6-kinase (EC 2.7.1.159, Ins(1,3,4)P3 5/6-kinase, inositol trisphosphate 5/6-kinase) is an enzyme with systematic name ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- (1) ATP + 1D-myo-inositol 1,3,4-trisphosphate ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
- (2) ATP + 1D-myo-inositol 1,3,4-trisphosphate ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate
| inositol-1,3,4-trisphosphate 5/6-kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.159 | ||||||||
| CAS no. | 288307-53-9 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In humans, this enzyme, along with EC 2.7.1.127 (inositol-trisphosphate 3-kinase), EC 2.7.1.140 (inositol-tetrakisphosphate 5-kinase) and EC 2.7.1.158 (inositol pentakisphosphate 2-kinase) is involved in the production of inositol hexakisphosphate (InsP6).
