Insulin degludec/insulin aspart
Combination medication
From Wikipedia, the free encyclopedia
Insulin degludec/insulin aspart, sold under the brand name Ryzodeg, is a fixed-dose combination medication for the treatment of diabetes mellitus.[6][7][8][9] It contains insulin degludec and insulin aspart.[6] It is given as an injection under the skin in the abdominal wall (at the front of the waist), upper arm or thigh.[6]
| Combination of | |
|---|---|
| Insulin degludec | Long-acting human insulin analog |
| Insulin aspart | Fast-acting human insulin analog |
| Clinical data | |
| Trade names | Ryzodeg |
| AHFS/Drugs.com | Professional Drug Facts |
| Pregnancy category | |
| Routes of administration | Subcutaneous injection |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
The most frequently reported side effect is hypoglycemia (low blood glucose levels).[6]
It was approved for medical use in the European Union in January 2013,[6] and in Australia in November 2017.[2]
Medical uses
Insulin degludec/insulin aspart is indicated for the treatment of diabetes mellitus in adults, adolescents and children from the age of two years.[6]
Insulin degludec and insulin aspart are slightly different from human insulin.[6] The differences mean that insulin degludec is absorbed more slowly by the body.[6] This means it has a long duration of action.[6] Meanwhile, insulin aspart is absorbed faster by the body than human insulin, and therefore it starts to work as soon as it is injected and has a short duration of action.[6]
