Health first announced "Isn't Everyone" on social media on 3 May 2021, discussing the song in more detail in an interview posted by journalist David Farrier on his Webworm blog the same day.[1][2] Frontman Jake Duzsik recounted the experience of working with Reznor for the first time since Health opened for Nine Inch Nails in 2008:
"I had not heard from him in a really long time, but I knew if I sent him an email and he was busy, he'd be busy and he just wouldn't respond, or he'd respond and say 'I'm busy.' [...] We sent him a demo and we did it very purposefully, where we sent something that was very skeletal. Because if you sent mostly a done track, that is not a collaboration — you are asking someone to guest on it. And the thing that ended up being really remarkable on it was we have done a lot of these collaborations now, and there can be a fair amount of awkwardness and not knowing — getting comfortable with your bandmates takes time — so you never know what it's going to be like. But Atticus and Trent put in more effort and more time — we did conference calls! They take everything they do very seriously so it was very deliberate, with a lot of attention to detail."[2]
Duzsik also described the themes and inspiration behind the song:
"I think at the time it was written — part of the reason we wanted it to come out so quickly, is that being an American in America, we were in the middle of Trumpocolypse [sic] and George Floyd and so there is some pretty poignant messaging relating to that specific experience."[2]