Let Xθ be a family of probability distributions on the real line indexed by the real parameter θ, and satisfying certain regularity conditions. Then

where
is the convex conjugate of the cumulant-generating function of
and
is the first moment of 
The left side of this inequality can be simplified as follows:
which is half the Fisher information of the parameter θ.
The right side of the inequality can be developed as follows:
This supremum is attained at a value of t=τ where the first derivative of the cumulant-generating function is
but we have
so that
Moreover,

We have:
which can be rearranged as:
