H2AFY2

MACROH2A2
Identifiers
Aliases	MACROH2A2, macroH2A2, H2A histone family member Y2, H2AFY2, macroH2A.2 histone
External IDs	OMIM: 616141; MGI: 3037658; GeneCards: MACROH2A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XD7
Gene location (Human)
Chr.	Chromosome 10 (human)
End	70,112,282 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	61,619,926 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; epithelium of colon; ; gingival epithelium; ; cerebellar vermis; ; pancreatic epithelial cell; ; islet of Langerhans; ; epithelium of esophagus; ; hair follicle; ; cerebellar hemisphere;
	Top expressed in
	genital tubercle; ; tail of embryo; ; neural tube; ; ventricular zone; ; maxillary prominence; ; ganglionic eminence; ; mandibular prominence; ; medial ganglionic eminence; ; otic placode; ; abdominal wall;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein heterodimerization activity; chromatin DNA binding;
Cellular component	ESC/E(Z) complex; nucleoplasm; chromosome; nucleosome; chromatin; extracellular exosome; Barr body; nucleus;
Biological process	nucleosome assembly; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I; positive regulation of keratinocyte differentiation; dosage compensation; negative regulation of transcription by RNA polymerase II; establishment of protein localization to chromatin; brain development; negative regulation of gene expression, epigenetic; regulation of cell growth; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55506
	404634
	ENSG00000099284
	ENSMUSG00000020086
	Q9P0M6
	Q8CCK0
	NM_018649
	NM_207000
	NP_061119
	NP_996883
	Wikidata
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