CBARA1

Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.^[5][6]

AliasesMICU1, CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC

External IDsOMIM: 605084; MGI: 2384909; GeneCards: MICU1

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 10 (human)^[1]

Quick facts MICU1, Identifiers ...

MICU1
Identifiers
Aliases	MICU1, CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC
External IDs	OMIM: 605084; MGI: 2384909; GeneCards: MICU1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4NSC, 4NSD
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q22.1 Start 72,367,340 bp[1] End 72,626,131 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B4 Start 59,538,299 bp[2] End 59,699,954 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon cerebellar hemisphere right hemisphere of cerebellum right adrenal cortex monocyte left adrenal gland right frontal lobe gastrocnemius muscle left adrenal cortex prefrontal cortex Top expressed in intestinal villus neural layer of retina dentate gyrus of hippocampal formation granule cell granulocyte pyloric antrum lens mucous cell of stomach zygote duodenum muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding metal ion binding protein binding identical protein binding protein heterodimerization activity Cellular component calcium channel complex membrane mitochondrial intermembrane space intracellular anatomical structure mitochondrion uniplex complex integral component of mitochondrial membrane integral component of membrane mitochondrial inner membrane Biological process defense response calcium ion import mitochondrial calcium ion homeostasis ion transport calcium import into the mitochondrion positive regulation of mitochondrial calcium ion concentration protein homooligomerization calcium ion transport mitochondrial calcium ion transmembrane transport regulation of cellular hyperosmotic salinity response Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 10367 216001 Ensembl ENSG00000107745 ENSMUSG00000020111 UniProt Q9BPX6 Q8VCX5 RefSeq (mRNA) NM_001195518 NM_001195519 NM_006077 NM_001363513 NM_001291442 NM_001291443 NM_144822 NM_001359267 RefSeq (protein) NP_001182447 NP_001182448 NP_006068 NP_001350442 NP_001278371 NP_001278372 NP_659071 NP_001346196 Location (UCSC) Chr 10: 72.37 – 72.63 Mb Chr 10: 59.54 – 59.7 Mb PubMed search [3] [4]
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