Mitochondrial ribosomal protein S26

28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesMRPS26, C20orf193, GI008, MRP-S13, MRP-S26, MRPS13, NY-BR-87, RPMS13, dJ534B8.3, mitochondrial ribosomal protein S26

External IDsOMIM: 611988; MGI: 1333830; HomoloGene: 12778; GeneCards: MRPS26; OMA:MRPS26 - orthologs

Chr.Chromosome 20 (human)^[1]

Quick facts MRPS26, Available structures ...

MRPS26
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3J9M
Identifiers
Aliases	MRPS26, C20orf193, GI008, MRP-S13, MRP-S26, MRPS13, NY-BR-87, RPMS13, dJ534B8.3, mitochondrial ribosomal protein S26
External IDs	OMIM: 611988; MGI: 1333830; HomoloGene: 12778; GeneCards: MRPS26; OMA:MRPS26 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 3,046,052 bp[1] End 3,048,250 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 F1 Start 130,405,662 bp[2] End 130,410,615 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary right lobe of liver myocardium of left ventricle Brodmann area 9 right adrenal gland skin of arm left adrenal gland left adrenal cortex mucosa of transverse colon right adrenal cortex Top expressed in supraoptic nucleus hair follicle yolk sac proximal tubule right kidney fossa renal corpuscle condyle facial motor nucleus external carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding Cellular component mitochondrial inner membrane ribosome mitochondrial small ribosomal subunit nucleoplasm mitochondrion Biological process peptide biosynthetic process mitochondrial translational elongation mitochondrial translational termination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64949 99045 Ensembl ENSG00000125901 ENSMUSG00000037740 UniProt Q9BYN8 Q80ZS3 RefSeq (mRNA) NM_030811 NM_207207 RefSeq (protein) NP_110438 NP_997090 Location (UCSC) Chr 20: 3.05 – 3.05 Mb Chr 2: 130.41 – 130.41 Mb PubMed search [3] [4]
Wikidata
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene.^[6]