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Oxford Nanopore Technologies

U.K.-based nanopore sequencing company From Wikipedia, the free encyclopedia

Oxford Nanopore Technologies plc is a UK-based company which develops and sells nanopore-based molecular sensing technology for the real-time analysis of DNA and RNA.[2][3][4] Its platform includes sequencing devices, consumables and software used across research, applied and clinical markets.[5][6][7] It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index.[8]

Quick facts Type, Traded as ...
Oxford Nanopore Technologies plc
TypePublic limited company
ISINGB00BP6S8Z30
IndustryNanopore sequencing
Founded2005; 21 years ago (2005)
Founders
Headquarters,
Key people
  • Duncan Tatton-Brown (Chair)
  • Francis Van Parys (CEO)
RevenueIncrease £223.9 million (2025)[1]
Decrease £(155.3) million (2025)[1]
Increase £(145.2) million (2025)[1]
Websitenanoporetech.com
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History

The company was founded in 2005 as a spin-out from the University of Oxford by Hagan Bayley,[9] Gordon Sanghera, and Spike Willcocks, with seed funding from the IP Group.[10] The company made an initial public offering on the London Stock Exchange on 30 September 2021, under the ticker ONT.[11]

In March 2016 the company announced a chemistry upgrade to its nanopore sequencing product 'R9', using a protein nanopore in collaboration with the laboratory of Han Remaut (VIB/Vrije Universiteit Brussel).[12] The company stated in a webcast that R9 is designed to improve error rates and yield.[13]

NASA astronaut Kate Rubins with a MinION sequencer on the ISS in August 2016.

In December 2025, the company announced that Francis Van Parys would succeed Gordon Sanghera as CEO.[14] Prior to joining Oxford Nanopore, he was President and CEO of Radiometer and held senior leadership roles at Cytiva and GE Healthcare.[14]

Products

Top view of a closed Oxford Nanopore Technologies MinION sequencer showing how it is small enough to be held in one hand

The main products of Oxford Nanopore are:

  • MinION:[15][16][17] this harmonica-sized portable protein nanopore sequencing USB device has been commercially available since May 2015.[18]
  • GridION: this desktop device has been commercially available since March 2017.[19] The device processes up to five MinION flow cells and enables generation of up to 100 Gb of data per run.[20]
  • PromethION: a desktop device for sequencing of native DNA or RNA samples.[21] The device contains channels for 144,000 nanopores (in comparison to MinION’s 512)[22] and delivers up to 290 Gb of data per flow cell.[23]
  • PromethION 24: this device is a nanopore sequencing platform released in 2019 for DNA and RNA sequencing projects[24]. It 24 flow cells which can be run independently.[25]
  • EPI2ME: a procut for customers with limited computational experience to process data without high-performance computing resources and programming expertise.[26][27]

These products are intended to be used for the analysis of DNA, RNA, proteins and small molecules with a range of applications in personalized medicine, Agricultural science and scientific research.[28]

References

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