Mitochondrial 2-oxoglutarate/malate carrier protein

SLC25A11
Identifiers
Aliases	SLC25A11, OGC, SLC20A4, solute carrier family 25 member 11, PGL6
External IDs	OMIM: 604165; MGI: 1915113; GeneCards: SLC25A11
Gene location (Human)
Chr.	Chromosome 17 (human)
End	4,940,053 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	70,538,305 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; muscle of thigh; ; right auricle of heart; ; left ventricle; ; gastrocnemius muscle; ; body of tongue; ; mucosa of transverse colon; ; right frontal lobe; ; prefrontal cortex; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	extraocular muscle; ; right ventricle; ; interventricular septum; ; digastric muscle; ; myocardium of ventricle; ; plantaris muscle; ; cardiac muscle tissue of left ventricle; ; temporal muscle; ; muscle of thigh; ; sternocleidomastoid muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding; oxoglutarate:malate antiporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; mitochondrion; nucleus; mitochondrial inner membrane;
Biological process	gluconeogenesis; alpha-ketoglutarate transport; mitochondrial transport; transport; transmembrane transport; malate transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	8402
	67863
	ENSG00000108528
	ENSMUSG00000014606
	Q02978
	Q9CR62
	NM_003562; NM_001165417; NM_001165418
	NM_024211
	NP_001158889; NP_001158890; NP_003553
	NP_077173
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.^[5]^[6]^[7] Inactivating mutations in this gene predispose to metastasic paraganglioma.^[8]