N-sec-Butyltryptamine

Psychoactive drug From Wikipedia, the free encyclopedia

N-sec-Butyltryptamine (NsBT) is a psychoactive drug of the tryptamine family related to psychedelics like dimethyltryptamine (DMT).[1][2]

Other namesNsBT; NSBT
ATC code
  • None
Quick facts Clinical data, Other names ...
NsBT
Clinical data
Other namesNsBT; NSBT
Routes of
administration
Oral[1][2]
Drug classPsychoactive drug[1][2]
ATC code
  • None
Pharmacokinetic data
Duration of action"Short"[1]
Identifiers
  • N-[2-(1H-indol-3-yl)ethyl]butan-2-amine
PubChem CID
ChemSpider
Chemical and physical data
FormulaC14H20N2
Molar mass216.328 g·mol−1
3D model (JSmol)
  • CCC(C)NCCC1=CNC2=CC=CC=C21
  • InChI=1S/C14H20N2/c1-3-11(2)15-9-8-12-10-16-14-7-5-4-6-13(12)14/h4-7,10-11,15-16H,3,8-9H2,1-2H3
  • Key:WDWNZOAFDWLAGZ-UHFFFAOYSA-N
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Use and effects

NsBT was briefly described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).[1] According to Shulgin, NsBT is active at a dose of 25 to 75 mg orally and has a short-lived duration.[1][2] Its effects included a generalized and somewhat diffuse intoxication, intellectual excitement, modest sensory enhancements, and "a lot of erotic horniness".[1] However, no "plus-three" ratings occurred on the Shulgin Rating Scale.[1]

Shulgin has said that along with N-tert-butyltryptamine (NtBT), it is one of only two N-mono-substituted tryptamines with known psychoactivity.[1] He also said that N-mono-substituted tryptamines might be GHB-like intoxicants devoid of psychedelic effects.[1] However, N-methyltryptamine (NMT) has been reported to produce psychedelic effects.[1][3][4]

Chemistry

Analogues

Analogues of NsBT include 5-MeO-NsBT, N-methyltryptamine (NMT), N-ethyltryptamine (NET), N-isopropyltryptamine (NiPT), N-benzyltryptamine (NBnT), N-methyl-N-sec-butyltryptamine (MsBT), among others.[1]

Society and culture

Canada

NsBT is not a controlled substance in Canada as of 2025.[5]

See also

References

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