Nuclear protein
Proteins found in the cell nucleus
From Wikipedia, the free encyclopedia
A nuclear protein is a protein found in the cell nucleus.[1] Proteins are transported inside the nucleus with they help of the nuclear pore complex, which acts a barrier between cytoplasm and nuclear membrane. Many nuclear proteins contain positively charged amino acids such as Lysine and Arginine which acts as a signal to allow the protein to get transported into the nucleus while maintaining their fold.[citation needed] The import and export of proteins through the nuclear pore complex plays a fundamental role in gene regulation and other biological functions.[2][3]
The Nuclear Protein Database (NPD) is a database of around 1,000 proteins localized to the vertebrate cell nucleus. Proteins are searchable by name, motif, nuclear compartment or a keyword term.[4][5]
