Phospholipid transfer protein

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

Phospholipid transfer protein is a protein that in humans is encoded by the PLTP gene.

AliasesPLTP, BPIFE, HDLCQ9, phospholipid transfer protein
End45,912,155 bp[1]
Quick facts PLTP, Identifiers ...
PLTP
Identifiers
AliasesPLTP, BPIFE, HDLCQ9, phospholipid transfer protein
External IDsMGI: 103151; HomoloGene: 4536; GeneCards: PLTP; OMA:PLTP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_182676
NM_001242920
NM_001242921
NM_006227

NM_011125

RefSeq (protein)

NP_001229849
NP_001229850
NP_006218
NP_872617

NP_035255

Location (UCSC)Chr 20: 45.9 – 45.91 MbChr 2: 164.68 – 164.7 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.[5]

Interactions

PLTP has been shown to interact with Apolipoprotein A1[6] and APOA2.[6]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.[§ 1]

[[File:
Statin_Pathway_WP430go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to article
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Statin_Pathway_WP430go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to article
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Statin pathway edit
  1. The interactive pathway map can be edited at WikiPathways: "Statin_Pathway_WP430".

References

Further reading

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