Protein phosphatase methylesterase-1

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The enzyme protein phosphatase methylesterase-1 (EC 3.1.1.89, PME-1, PPME1; systematic name (phosphatase 2A protein)-leucine ester acylhydrolase[1][2] catalyses the reaction

[phosphatase 2A protein]-leucine methyl ester + H2O [phosphatase 2A protein]-leucine + methanol

A key regulator of protein phosphatase 2A.

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