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Protein phosphatase with EF-hand domain 2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Protein phosphatase with EF-hand domain 2 is a protein that in humans is encoded by the PPEF2 gene.[5]

AliasesPPEF2, PPP7CB, protein phosphatase with EF-hand domain 2
End75,902,571 bp[1]
Quick facts PPEF2, Identifiers ...
PPEF2
Identifiers
AliasesPPEF2, PPP7CB, protein phosphatase with EF-hand domain 2
External IDsOMIM: 602256; MGI: 1342304; GeneCards: PPEF2
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
3.1.3.16
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006239
NM_152933
NM_152934

NM_011148

RefSeq (protein)

NP_006230

NP_035278

Location (UCSC)Chr 4: 75.86 – 75.9 MbChr 5: 92.37 – 92.4 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. [provided by RefSeq, Jul 2008].

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