SLC45A3

SLC45A3
Identifiers
Aliases	SLC45A3, IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST, solute carrier family 45 member 3
External IDs	OMIM: 605097; MGI: 1922082; GeneCards: SLC45A3
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,680,509 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	131,910,707 bp
RNA expression pattern
	Top expressed in
	prostate; ; C1 segment; ; oocyte; ; nasal epithelium; ; secondary oocyte; ; mucosa of ileum; ; right lobe of liver; ; spleen; ; inferior ganglion of vagus nerve; ; mucosa of transverse colon;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; gastric mucosa; ; pyloric antrum; ; mucous cell of stomach; ; epithelium of stomach; ; egg cell; ; lumbar spinal ganglion; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	sucrose:proton symporter activity; sugar transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane;
Biological process	transmembrane transport; sucrose transport; positive regulation of glucose metabolic process; positive regulation of fatty acid biosynthetic process; regulation of oligodendrocyte differentiation; hexose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	85414
	212980
	ENSG00000158715
	ENSMUSG00000026435
	Q96JT2
	Q8K0H7
	NM_033102
	NM_001177628; NM_145977
	NP_149093
	NP_001171099; NP_666089
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 45 member 3 (SLC45A3), also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by the SLC45A3 gene.^[5]^[6]^[7]

AliasesSLC45A3, IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST, solute carrier family 45 member 3

External IDsOMIM: 605097; MGI: 1922082; GeneCards: SLC45A3

Chr.Chromosome 1 (human)^[1]

End205,680,509 bp^[1]

Quick facts Identifiers, Aliases ...

Close

SLC45A3 is expressed in a prostate-specific manner by normal tissues and at a significantly lower level in prostate tumor cell lines. Treatment of prostate cancer cell lines with androgens upregulates the expression of SLC45A3.^[7]

[5]

[6]

[7]

[1]

[2]

[3]

[4]

SLC45A3

Regulation

References

Further reading

Related Articles

Timelines

Top Qs

Fact Checks

Related Articles

"Prediction of gene function by genome-scale expression analysis: prostate cancer-associated genes"

"Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like 7 gene, regulates prostein translation and invasiveness of prostate cancer LNCaP cells"

"N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer"

"Prevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort"

"Transcriptome sequencing to detect gene fusions in cancer"

"Identification of an HLA-A*0201-restricted T-cell epitope derived from the prostate cancer-associated protein prostein"