60S ribosomal protein L37

60S ribosomal protein L37 is a protein that in humans is encoded by the RPL37 gene.^[5][6][7]

AliasesRPL37, L37, ribosomal protein L37

External IDsOMIM: 604181; MGI: 1914531; GeneCards: RPL37

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 5 (human)^[1]

Quick facts RPL37, Identifiers ...

RPL37
Identifiers
Aliases	RPL37, L37, ribosomal protein L37
External IDs	OMIM: 604181; MGI: 1914531; GeneCards: RPL37
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 4D67, 4UJC, 4D5Y, 4UJE, 4UJD, 4V5Z
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p13.1 Start 40,825,262 bp[1] End 40,835,222 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 A1 Start 5,146,127 bp[2] End 5,148,622 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium nipple urethra human penis parietal pleura pylorus palpebral conjunctiva caput epididymis mucosa of sigmoid colon visceral pleura Top expressed in embryo embryo lip ventricular zone dentate gyrus of hippocampal formation granule cell yolk sac primary visual cortex superior frontal gyrus granulocyte muscle of thigh More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding rRNA binding structural constituent of ribosome RNA binding Cellular component ribosome cytosol intracellular anatomical structure cytosolic large ribosomal subunit synapse Biological process SRP-dependent cotranslational protein targeting to membrane viral transcription nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translational initiation protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 6167 67281 Ensembl ENSG00000145592 ENSMUSG00000041841 UniProt P61927 Q9D823 RefSeq (mRNA) NM_000997 NM_026069 RefSeq (protein) NP_000988 NP_080345 Location (UCSC) Chr 5: 40.83 – 40.84 Mb Chr 15: 5.15 – 5.15 Mb PubMed search [3] [4]
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]