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40S ribosomal protein S30

Human protein From Wikipedia, the free encyclopedia

40S ribosomal protein S30 is a protein that in humans is encoded by the FAU gene.[5][6]

AliasesFAU, FAU1, Fub1, Fubi, MNSFbeta, S30, asr1, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed, ubiquitin like and ribosomal protein S30 fusion, FAU ubiquitin like and ribosomal protein S30 fusion, RPS30
External IDsOMIM: 134690; MGI: 102547; GeneCards: FAU
PDBOrtholog search: PDBe RCSB
Quick facts FAU, Identifiers ...
FAU
Identifiers
AliasesFAU, FAU1, Fub1, Fubi, MNSFbeta, S30, asr1, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed, ubiquitin like and ribosomal protein S30 fusion, FAU ubiquitin like and ribosomal protein S30 fusion, RPS30
External IDsOMIM: 134690; MGI: 102547; GeneCards: FAU
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001997

NM_001160239
NM_001190436
NM_007990

RefSeq (protein)

NP_001988

NP_001153711
NP_001177365
NP_032016

Location (UCSC)Chr 11: 65.12 – 65.12 MbChr 19: 6.11 – 6.11 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein FUBI at the N-terminus and ribosomal protein S30 at the C-terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.[6]

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