Capeserod

Capeserod (INN;^[1] development code SL65.0155) is a selective 5-HT₄ receptor partial agonist with K_i = 0.6 nM and IA = 40–50% (relative to serotonin).^[2] It potently enhances cognition, learning, and memory,^{[2][3][4][5][6][7]} and also possesses antidepressant effects.^[8] Capeserod was in phase II clinical trials around 2004–2006 for the treatment of memory deficits and dementia but no new information has surfaced since and it appears to have been abandoned.^[9][10]

ATC code

• None

CAS Number

• 769901-96-4
  191023-43-5 (HCl)

PubChem CID

• 9805719

IUPHAR/BPS

• 29

Quick facts Clinical data, ATC code ...

Capeserod

Clinical data
ATC code	None
Identifiers
IUPAC name 5-(5-Amino-6-chloro-2,3-dihydro-1,4-benzodioxin-8-yl)-3-[1-(2-phenylethyl)piperidin-4-yl]-1,3,4-oxadiazol-2-one
CAS Number	769901-96-4 191023-43-5 (HCl)
PubChem CID	9805719
IUPHAR/BPS	29
ChemSpider	7981479
UNII	8163770L8P
ChEMBL	ChEMBL2027925
CompTox Dashboard (EPA)	DTXSID60998277
Chemical and physical data
Formula	C23H25ClN4O4
Molar mass	456.93 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCC1N2C(=O)OC(=N2)C3=CC(=C(C4=C3OCCO4)N)Cl)CCC5=CC=CC=C5
InChI InChI=1S/C23H25ClN4O4/c24-18-14-17(20-21(19(18)25)31-13-12-30-20)22-26-28(23(29)32-22)16-7-10-27(11-8-16)9-6-15-4-2-1-3-5-15/h1-5,14,16H,6-13,25H2 Key:MDBNTXARNGRHEV-UHFFFAOYSA-N

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