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Somatostatin receptor 3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.[5][6]

AliasesSSTR3, SS-3-R, SS3-R, SS3R, SSR-28, Somatostatin receptor 3
External IDsOMIM: 182453; MGI: 98329; GeneCards: SSTR3
End37,212,477 bp[1]
Quick facts SSTR3, Identifiers ...
SSTR3
Identifiers
AliasesSSTR3, SS-3-R, SS3-R, SS3R, SSR-28, Somatostatin receptor 3
External IDsOMIM: 182453; MGI: 98329; GeneCards: SSTR3
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001051
NM_001278687

NM_009218
NM_001356961

RefSeq (protein)

NP_001042
NP_001265616

NP_033244
NP_001343890

Location (UCSC)Chr 22: 37.2 – 37.21 MbChr 15: 78.42 – 78.43 Mb
PubMed search[3][4]
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Function

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.[6]

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