Mussa-Ivaldi’s research combines experimental methods with the application of computational principles. His experimental
work has been influential for the study of arm biomechanics and, in particular, motor learning in human subjects. He has
also studied motor primitives in the frog's spinal cord that are a central issue in many theories of motor control.
Sandro Mussa-Ivaldi's theoretical work has focused on the analysis of redundant kinematics in human subjects. He has asked
how a variety of movement patterns and control strategies can be constructed from the superposition of a set of basis fields. Of particular theoretical importance is his discovery of how pseudoinverses of
Jacobians can be computed so that integrability is always a given. In some more recent work, Sandro Mussa-Ivaldi has applied computational ideas to the design of brain machine interfaces. He and his collaborators have developed the first neurorobotic system in which a neural preparation in-vitro - the brainstem of a Lamprey - controls the behavior of a mobile-robot through a closed-loop interaction. Recent research in the lab of Dr. Mussa-Ivaldi addresses clinical questions where computational insights can be used to better the lives of persons with disabilities.