N-acetylneuraminate epimerase

N-acetylneuraminate epimerase (EC 5.1.3.24, sialic acid epimerase, N-acetylneuraminate mutarotase, sialic acid mutarotase, YjhT, NanM) is an enzyme with systematic name N-acetyl-alpha-neuraminate 2-epimerase.^[1] This enzyme catalyses the following chemical reaction

N-acetyl-alpha-neuraminate ${\displaystyle \rightleftharpoons }$ N-acetyl-beta-neuraminate

Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages.