Phenylethylpyrrolidine
Chemical compound
From Wikipedia, the free encyclopedia
1-(2-Phenylethyl)pyrrolidine (PEP) is a chemical compound of the phenethylamine family. It is an analogue of 2-phenylethylamine where the amine has been replaced by a pyrrolidine ring.
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| Preferred IUPAC name
1-(2-Phenylethyl)pyrrolidine | |
| Identifiers | |
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| Properties | |
| C12H17N | |
| Molar mass | 175.275 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Derivatives
The α-methyl (i.e., amphetamine derivative is 1-(α-methylphenethyl)pyrrolidine (MPEP), the β-keto derivative is phenacylpyrrolidine, and the combined α-methyl and β-keto (i.e., cathinone) derivative is α-pyrrolidinopropiophenone (α-PPP).[1] Prolintane is the α-propyl derivative of PEP.[1]
PEP is the base chemical structure for a series of stimulant drugs, including:[1]
All of these compounds differ from PEP in that the alpha carbon is extended and a ketone is attached to the beta carbon (with the exception of prolintane), among other modifications.[1]
A cyclized phenethylamine and 2-aminoindane derivative is Pyr-AI ((2-indanyl)pyrrolidine).[2] It is the analogue of 2-aminoindane (2-AI) in which the amine has been replaced with a pyrrolidine group.[2] The drug has been described as having strong and long-lasting amphetamine-like effects in rodents.[2][3]