Suloctidil

Chemical compound From Wikipedia, the free encyclopedia

Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.[1]:118–121[2][3]

ATC code
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Suloctidil
Clinical data
ATC code
Identifiers
  • 1-[4-(isopropylthio)phenyl]-2-(octylamino)propan-1-ol
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.053.920 Edit this at Wikidata
Chemical and physical data
FormulaC20H35NOS
Molar mass337.57 g·mol−1
3D model (JSmol)
  • CCCCCCCCNC(C)C(C1=CC=C(C=C1)SC(C)C)O
  • InChI=1S/C20H35NOS/c1-5-6-7-8-9-10-15-21-17(4)20(22)18-11-13-19(14-12-18)23-16(2)3/h11-14,16-17,20-22H,5-10,15H2,1-4H3
  • Key:BFCDFTHTSVTWOG-UHFFFAOYSA-N
  (verify)
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Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US.[4] However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.[5]:251

References

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